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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMOX1
All Species:
37.88
Human Site:
S142
Identified Species:
83.33
UniProt:
P09601
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P09601
NP_002124.1
288
32819
S142
T
R
Y
L
G
D
L
S
G
G
Q
V
L
K
K
Chimpanzee
Pan troglodytes
XP_001155421
265
30338
T124
R
L
H
E
V
G
R
T
E
P
E
L
L
V
A
Rhesus Macaque
Macaca mulatta
XP_001113241
323
36340
S177
T
R
Y
L
G
D
L
S
G
G
Q
M
L
K
K
Dog
Lupus familis
XP_853145
338
38010
S192
T
R
Y
L
G
D
L
S
G
G
Q
V
L
K
K
Cat
Felis silvestris
Mouse
Mus musculus
P14901
289
32910
S142
T
R
Y
L
G
D
L
S
G
G
Q
V
L
K
K
Rat
Rattus norvegicus
P06762
289
32987
S142
T
R
Y
L
G
D
L
S
G
G
Q
V
L
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520273
701
77374
S551
T
R
Y
L
G
D
L
S
G
G
Q
I
L
K
K
Chicken
Gallus gallus
P14791
296
33491
S145
T
R
Y
L
G
D
L
S
G
G
Q
V
L
K
K
Frog
Xenopus laevis
NP_001083510
288
32873
S145
T
R
Y
L
G
D
L
S
G
G
Q
V
L
K
K
Zebra Danio
Brachydanio rerio
XP_002661145
318
35281
S166
T
R
Y
M
G
D
L
S
G
G
Q
V
L
R
K
Tiger Blowfish
Takifugu rubipres
O73688
277
31192
H136
N
P
E
Y
L
I
A
H
A
Y
T
R
Y
L
G
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.1
85.1
73.9
N.A.
82
79.9
N.A.
27.8
61.8
60.7
43.7
47.9
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
88.1
87
78.6
N.A.
91
88.9
N.A.
34.2
75
73.6
59.4
67
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
100
N.A.
100
100
N.A.
93.3
100
100
86.6
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
100
100
100
100
0
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
82
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
10
0
0
0
0
10
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
82
10
0
0
82
82
0
0
0
0
10
% G
% His:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
73
82
% K
% Leu:
0
10
0
73
10
0
82
0
0
0
0
10
91
10
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
82
0
0
0
0
% Q
% Arg:
10
82
0
0
0
0
10
0
0
0
0
10
0
10
0
% R
% Ser:
0
0
0
0
0
0
0
82
0
0
0
0
0
0
0
% S
% Thr:
82
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
64
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
82
10
0
0
0
0
0
10
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _